Increased plasma concentration of epidermal growth factor in female patients with non-toxic nodular goitre

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Increased plasma concentration of epidermal growth factor in female patients with non-toxic nodular goitre.

OBJECTIVE Epidermal growth factor (EGF) is believed to be one of the most potent growth factors for the thyroid gland. DESIGN AND METHODS We tested plasma EGF concentrations (radioreceptor method) in patients with non-toxic nodular goitre (NNG). Blood samples from patients with NNG were collected on the day before the surgery, during subtotal thyroidectomy (sTx)--from peripheral and thyroid v...

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Symptoms of non-toxic nodular goitre.

IN 1932, Cecil Joll, in his book "Diseases of the Thyroid Gland" emphasised that "although respiratory symptoms due to tracheal compression and alteration of voice were common", dysphagia was a "decidedly rare feature of simple goitre". Since then there has been little documentation on the subject. The following is an account of the symptoms found in a series of patients undergoing surgery for ...

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Non-toxic nodular goitre and thyroid nodules

The present opinions on the therapy with L-thyroxine (L-T4) of non-toxic multinodular, as well as of non-toxic thyroid nodules are rather divergent. This treatment is based on the suppression of TSH secretion from the pitu-

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Non-toxic Goitre in Males.

Occult bleeding from the gastro-intestinal tract for which no cause can be found is not uncommon in cases of iron-deficiency anaemia. A follow-up study of 68 patients in whom this diagnosis was made after initial investigation has revealed only 17 in whom some cause of bleeding became apparent (in 12 aspirin ingestion, in two bleeding piles, in one a gastric ulcer, in one a possible carcinoma o...

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ژورنال

عنوان ژورنال: European Journal of Endocrinology

سال: 1998

ISSN: 0804-4643,1479-683X

DOI: 10.1530/eje.0.1380388